So, I have noticed since I've been off my Cymbalta (pdoc took me off once BP dx due to it being a mania trigger). Here is my problem, I can't deal with stress anymore AT ALL! I get angry and irritable at the slightest thing. My anxiety and OCD is bad since I've been off of it. I'm so tired of having trade-offs with this illness. I'm so tired of not being stable and not feeling normal. I'm not manic but I'm anxious and my OCD is bad. So sick of it! Anybody relate?