Hello Melmo: Well... my circumstances are entirely different from yours. But I do also struggle with allot of generalized anger & irritability. I'm also no longer on med's. Most recently I was on the generic equivalent of Cymbalta. It was the best antidepressant I've taken, for me. But I changed health insurers & the out-of-pocket cost skyrocketed. So I went off of the med. All-in-all I'm glad I did. But I do think that, since then, my anger & irritability have been worse. I wish I had some concrete suggestions for you, but I don't. Personally, I practice walking meditation along with other self-help techniques I have learned from reading the books of the Buddhist nun Pema Chödrön. It keeps me going...