Seroquel is known to cause problems with diabetes, but it depends that may depend on the persons tendency toward it in the first place. That is the main bad side effect that I have heard about....thus, needing blood tests after awhile to make sure everything is ok with the blood.

The one strange thing that happens to me after taking any dose....even 25 mg, is that my nose gets stuffed up so bad, I can't breath through it & have to end up breathing through my mouth. It is a scarry feeling waking up & not being able to breath in the middle of the night (like when I have a really bad cold). It goes away as soon as the dose wears off. It happens everytime I take it & when I don't take it, my breathing is just fine....that is how I know it's an effect from the seroquel.

The other feeling is the groggyness the next morning only after a larger dose, but even with the small dose, I have a hard time getting going after taking it. I am just continue feeling so tired, I don't want to get up until is finally all wears off. Then I can start functioning until my next anxiety attack when I take another seroquel. It makes me so drousy I have to lay down & sleep it off, but then I feel relaxed & the anxiety goes away for awhile.

Those are the only side effects I have experienced or know of related to seroquel.
Debbie