I had every weird reaction in the book so I understand.Eventually I reached a point where weight gain had to just be accepted, although I think I'm starting metformin soon. But it took many years to get to the point that it was clozari or nothing and that would be true for you too. And the good news is that there are more drugs available than there were for me.

One you might want to ask about is loxapine. It's really old but is weight neutral and it worked well for me until causing a bad side effect (which I'm extremely susceptible to so unlikely to happen for you).

Thanks for asking about the clozaril. I'm better although I think I'm going to need to add some more. My mood is much better but I still have motivational issues and perhaps some depression lingering. But I'm still making slow steps and my therapist is pleased; he says my voice is finally emotive after months of not being. I caught some horrible throat infection from my germy nieces so that's not helping my motivation right now but it will pass.

I promise, something will help you. For me it was an MAOI and the the right dose of Seroquel (which wasn't a problem with weight until I was over 800 mg) and then I had some bad times then some ok times and then the last year has been terrible but it took a long time to reach any response. And hopefully my clozaril response lasts enough to be a response.

Hang in there.