Quote:
Originally Posted by qwerty68
I a lot of medication is used "off label", especially in psychiatry. I haven't heard of scopolamine being used for depression. All drugs have side-effects, here is one list.
Once a drug is approved by the FDA, most often drug companies don't want the added expense of getting it approved in another area. However, that doesn't mean that research stops, it is just research done elsewhere, including doctors offices.
There are anti-psychotics that are unapproved for depression but commonly used. I have read that SSRI's are being used off-label for some types of pain instead of opioids.
It certainly is worth talking to your doctor about. It might be helpful in finding a cause of your depression. Your experiences are interesting. Drugs like tricyclic meds actually inhibit acetylcholine, which scopolimine does so maybe it is not surprising it helped you. |
Thanks, @qwerty68
I was not certain how scopolamine affected acetylcholine. I was thinking of trying to use vitamins or changes in diet to help my brain, but I wasn't certain what scopolamine did to the acetylcholine in the brain. One article seemed to suggest that scopolamine concentrated the acetylcholine in the frontal lobes and depleted it from the muscles? (or maybe I have it backwards).
Anyway, I tried another patch today. At first I was afraid that it no longer worked, but after an hour I suddenly felt like a heavy weight had been removed. I felt very hopeful and content and I got a lot more work done than normal. I felt more like being around other people and trying to be nice to them. In the past, the effect seems to diminish over the three days that the patch it used. I feel really, really good when I first apply a patch.
I have a doctor's appointment in a few weeks, and I will mention the scopolamine.