I have the worst case of GERD any of the docs they send me to have ever seen. I asked about probiotics hoping that one might aid with digestion thus easing my symptoms. Every one of the docs and the two pharmacists I spoke to agreed probiotics work in the intestines. They can significantly improve waste removal, immunity, reduce yeast infections etc... but the only way they will help with digestion is if bacteria in your gut is off. But they all said that unless you've been on massive doses of antibiotics the chance of it being off is minuscule.