Hi and Welcome!.

I've become less tolerant with age, when it should be the opposite.
I don't think is completly bipolar related. How do you feel when the Dextro comes down?.
I was on Adderall for depression and the results were terrible. I had to take xanax after three or four hours to calm down. That at only 10 mgs. Some of us can't take upper period.
Good luck in your quest, and I hope you can,(as I have), benefit from our forum.