View Single Post
 
Old Apr 08, 2016, 03:31 PM
Icare dixit's Avatar
Icare dixit Icare dixit is offline
Magnate
 
Member Since: Feb 2016
Location: A version of earth
Posts: 2,626
Quote:
Originally Posted by pirilin View Post
Simply google: lamictal and lamotrigine difference.
No, I think (I also keep to scientific and regulator databases) that the research they use to "prove" a difference in efficacy, is research that always has to be done to prove bioequivalence or bioavailability of any generic drug, comparing between different generics and the original product.

Of course there are differences, but they are only important when switching from one brand to another, for some meds, to make sure that, say, 100 mg of lamotrigine of one brand works the same, mostly as strongly, as 100 mg of another. Some meds might "become" too toxic without changing the actual dose, just the brand.

But for lamotrigine this is not an issue.

I gave lithium as an example, because there switching may have direct negative effects. However, as we both said, measuring serum levels is the way to avoid toxicity, because individual differences matter more than excipients.
__________________
Mania kills cells. Brain cells die. Memories become more reduced conceptually, making more efficient use of limited means. Memories shape our reality. Our memories are more or less split in two by abstractions, conceptual reductions. Mood states with memories, concepts, attached. Memories of pain and those of joy. It causes instability, changeability. Fearing that will leave an emptiness between pain and joy and a greater divide.
See Me, Feel Me, Touch Me, Heal Me.
Thanks for this!
gina_re