Hey so I was put on Lithium 6 months ago n It doesnt help me at all. In fact doc says for last 3 months ive been in a bipolar depressive episode for the last 3 months. It just slowly got worse til I am now a big mess. I was on 900mg lithium n also takin abilify. Didnt work for me it made things worse. So doc put me on lamotrigine n lorazapam n wellbutrin while still on the other meds. Shes gonna slowly tapper down on old meds n slowly increase the new as needed. I gained a lot of weight on lithium also. Gained 10lbs just in 2 months. So to answer your question...yes you can b on mood stabilizers n anti depressants. U should really get on one fast if your slippin into depression. So far im likin this wellbutrin but im only on day 2. Hope this helps!!!