I just started Latuda recently, mostly for paranoia, just 40mg/day. I'm taking low doses of a lot of stuff and I feel great. I'm lucky enough to rarely feel a side effect. But I definitely felt a difference in my thoughts when I started Latua and my sleep got back on track. I was pretty hypomanic when I started it. I've read that even though it's advertised for depression, it could possibly be more effective in the treatment of mania. It's an antipsychotic. I need meds for mania, but the only thing to pull me out of depression was Transcendental Meditation.