I've heard it is important to keep them in their original bottle for legal reasons, but as many as I take in the morning, I just can't carry that many bottles in the morning to and from work and so I use a pill box. But it's really the only time I do that. And I take the train directly to and from work. Now if I was traveling a long distance that involves a longer train ride or a plane, I would keep them in their bottles like others have recommended.