I did it as an adult and my ex wife also did it when she came here.

In my case it was likely more easy. I had 14 days earlier finalized a VERY messy relationship (marriage) so I was basically a completely broken man. I also had the advantage though that I was "eased in to the new culture as I was in the military at the time. This allowed me to slowly adapt.

My biggest problem in the end, I wasnt really "at home" in either the American culture or my adopted culture (after 9 years). To this day I struggle with that (and I have been back in the US 19 years).

The very first thing you need to learn though is the local language. Without that you will become a miserable, paranoid person. I would even recommend you have at least a basic understanding of the language before you move there. Yes there might be many people who speak english, but you will never truely be accepted or understand the culture until you have a good grasp of the language!