I have found that I feel much better if I stick to a regular schedule, especially now that I'm working again. I take my night meds at around 8:30 or 9 and am asleep by 10 or 11 and wake up at 6:30 every morning even though I don't have to leave for work until 10am. It takes me awhile to wake up fully every morning because of the meds. When I wasn't working I had no schedule and found I wasn't feeling as well. Maybe you can take your saphris at 10pm and still be up by 9am. I don't take saphris, but my night meds put me to sleep pretty quickly most nights. Being on that regular routine of sleep has really helped. I'm rested and have more energy everyday. I also feel more stable. Good luck figuring out what works for you.