Hello will19: I don't know... from my perspective... things just change over time. Nothing ever stays the same... for better or worse... So from my perspective, what is important here is to recognize that what you're experiencing is simply the way life is.
Also, of course, it is possible that your depression is clouding your perspective. It is possible as well that you're unconsciously manifesting your depression to others & that they're steering clear of you as a result because they don't want to deal with it. So there are a variety of different possibilities here. Perhaps more than one is at play.
My personal perspective would be that perhaps you might consider trying to make a change in one area & see how that goes. I wouldn't recommend throwing the baby out with the bath water, as the saying goes. And as far as changing yourself goes... well... if there are things about yourself that you'd like to change, certainly by all means do what you can to try to be more the person you'd like to be. However, trying to change who you are now into some other type of person whom you imagine may fit in better within the various environments you frequent (i.e. work, church, & residence) seems to me to be a losing proposition. Even if you are successful at doing this now, you likely will be faced with doing it all over again the next time things seem to have taken another down turn. I wish you well...