Quote:
Originally Posted by Dontspeak
I smoke cigarettes too, and a lot when I'm stressed to manic. But my pdoc says those that use nicotine process their AP bc the liver is detoxifying the nicotine. So we clear our meds faster. Something to think about it. It's not only a stimulant, and addictive, but it's clearing our drugs faster! I hate that I smoke. But I love smoking. End of rant.
Life of Pi so good 
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Nicotine actually speeds up liver metabolism. That allows more of a med to be used. It is kept in the body for some time because it's used as a neuromodulator. It's not considered very foreign by the body.
However, cigarette smoke does contain other substances/particles which suppress liver metabolism.
The net effect is negative for cigarette smoke, but better with just nicotine.