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At 50 mg quetiapine (Seroquel) might. It could be the association of depression with being tired due to the antihistaminic effect that can make depression worse/persist. It may feel like depression and hence (maybe) become depression.
But all atypical antipsychotics are antidepressive, antidepressants as well as antipsychotics.
Changes in perception/perspective are more likely to maintain depression, making it worse or prolonging it, and antipsychotics make these changes less extreme.
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Mania kills cells. Brain cells die. Memories become more reduced conceptually, making more efficient use of limited means. Memories shape our reality. Our memories are more or less split in two by abstractions, conceptual reductions. Mood states with memories, concepts, attached. Memories of pain and those of joy. It causes instability, changeability. Fearing that will leave an emptiness between pain and joy and a greater divide.
See Me, Feel Me, Touch Me, Heal Me.
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