"“California rocket fuel” is a medical slang term for the combined administration of mirtazapine (a NaSSA) and venlafaxine (an SNRI).[1] This combination is usually used in the treatment of severe and/or treatment-resistant depression and may have efficacy superior to the MAOI tranylcypromine (though the advantage was not statistically significant in this study), with fewer side effects and better tolerability.[2] However, when used as an initial treatment, the mirtazapine and venlafaxine combination resulted in more than twice the remission rate of single antidepressant therapy with the SSRI fluoxetine."

There we go. There. We go.