Yes, I have lost 60 lbs after gaining A LOT of weight after starting all theses psych meds in my 20's (I'm 33 now). I wish I could show you my before and after pics... I look great now! You can do it!! Weight Watchers helped me the most because I tended to emotionally eat (especially sugar) to try to calm my anxiety and also gave myself permission to eat unhealthy things. Weight Watchers helped big-time with that. I'm planning on losing more weight, and I feel confident I can do it. I've taken many weight-gainers over the years and I really feel like they increase your appetite, but they don't keep you from being able to get control over your eating. Exercise is only 20% or less of weight-loss. Watching your diet is the number 1 way to lose weight. You may think you eat healthy, but you may be consuming too many calories. Try WW or some other calorie-counting system. Just make sure you are consuming the right amount of calories (I have noticed My Fitness Pal limits calories too much to an unhealthy low level). Good luck!!!! I will be happy to give you tips along the way.