Im about 20lbs overweight and it kills me. The pain makes every step I take feel terrible. I'm so sick all the time and my only hope is to get into better shape and hope it will take this fibro and arthritis pain away. I could not survive at 500lbs. My dad is about 100lbs overweight and it doesn't slow him down at all. I know a 400lb person who is in less pain and has more sex than me. So this answer will be unique to all of us and no way could I accept being 500lbs as an acceptable trade off. Most of the time I'm sane. Sometimes I'm not. I've been dealing with this forever. I don't want I'm dealing with. Weight and my body do not mix.