Although drinking isn't the best idea on medication, I try to only drink 1-2 glasses of wine, maybe a night or two a week. Then, maybe 3-4 here and there on a weekend, but not every week. Basically, I drink in moderation most of the time. I notice I drink much less than I used to ever since starting Lamictal. It makes me get to a point where I don't feel the desire to drink, or I won't feel too good. Back when I was on an SSRI years ago (which made me go crazy), I was drinking and craving large amounts of alcohol. I'm glad I don't drink as much anymore, although sometimes I wish my tolerance was a little bit better. On nights of heavier than usual drinking, I find myself not taking Seroquel since I do not find that to be a good combination at all and probably not that safe.