I used to take Zyprexa many years ago and I packed on the pounds, too. As a matter of fact, I haven't lost those pounds! I have been taking Saphris for around 5 years and have not gained any additional weight. Tastes nasty but works for me...I haven't had an episode since I've been taking it. I also sleep quite well on it, so I have to take it all at night. I hope that you find something that works!