I have taken zyprexa for 3 years very succesfully.Only problem was the sleeping or feeling very fatigued. after almost 3 years I finally realized it had almost everything to do with when I took it in relation to when I actually went to bed and how long I was able to sleep. I took it at 11pm every night and would sleep well into late morning. After some tinkering I found out that after about the 4th hour post ingestion it made me very sleepy. If I slept then I would sleep about 8 hours and wake rested with much more energy. If you take the zyprexa for the recommended time at first and some benefit but still tired trying tweaking the time you take it. If you have bad side effects or notice no impropvement please consider a different drug or combo. Best wishes. Hope I helped some.