Hello Everyone;

I'm currently taking a Lexapro / Wellbutrin combination for depression and anxiety, plus Remeron to help me sleep.

My Dx is pretty new, and my doc (I don't have a psychiatrist) and I are only beginning to understand my condition better. Lexapro and Wellbutrin are fine for some symptoms, but impulsivity and substance abuse haven't been tackled.

After my research, it appears Symbyax (Prozac plus Zyprexa) appears to be quite effective. However, it seems to me that these two drugs are quite strong and conducive to weight gain.

I'd like to suggest to my doc to put me on Zoloft and Abilify, given that both appear to have a higher tolerability profile and less adverse effects.

However, I'd also like to keep the Wellbutrin, since it works really well for me; and I'm afraid that the Zoloft / Abilify combo will make me too sleepy and prevent me to function normally at work and at home.

The Remeron is also fine for me; it's a very low dose, and I sleep well with it.

Would a 4-drug combination may just too much? Any thoughts?