That has not happened on Seroquel, although I am on a lower dose, primarily for anxiety at the moment. It is not really helping much with mood stabilization. At least it seems that way to me right now.

However, in the past I was on resperidal and it wasn't the greatest for me. I disappeared for several weeks and when I returned a friend got me to admit myself.

But on Zyprexa and Seroquel I've only really had issues with the dose being too low and can usually adjust before things get out of hand.