I found Latuda worked for depression within 7-10 days and better at 14 days.
quite a bit better at 21 days. My depression has been treatment-resistant otherwise.

I was in a prolonged mixed episode and as depression cleared, was left with hypomania, which is clearing up by slightly increasing Depakote.

Nausea only if took med without food, adequate calories. The calories give max absorption of Latuda, which should allow for a lesser dose. The food intake also happens to help with nausea.

literature states there is no proven efficacy above 60 mg. per day.

I am much more active, have more energy every day.

Latuda is on the list for QT prolongation. It is listed as one of the drugs with a lesser QT prolongation effect, yet has prolongation nonetheless. I also watch for drugs with QT prolongation, even though I am without heart disease. I, personally, decided to try Latuda, after reviewing its entire profile.

If you are out hiking, watch your hydration and electrolyte status. Stay as cool as possible. review all literature (professional) to be sure you understand all risks and precautions, especially heat exposure and heart-related info if this is a concern for you. Monitor your heart rate and symptoms if you try the med, esp in the heat.

Ask lots of questions of your pdoc and pharmacist.

I hope you enjoy your vacation!


WC