Wow, topomax, havenl't heard that name in awhile. There is a very rare side effect to that one, less than 2% of people on it get it... and I was one of them. Calcium Oxylate kidney stones. So bad in my case I required surgery. One lodged in my uretur and nearly caused my kidney to rupture - took emergency surgery to save my kidney, possibly my life. Like I said, it is a rare side effect, but just a reminder to everyone, make sure you read up on all possible side effects before taking anything. If you are on one that can cause these kinds of stones, get your blood tested for oxylate levels regularily.