Be careful with the Depo! Yeah, it's great stuff, works like a dream. But if you're on it too long it just draws the calcium right out of your bones! I was on it for nine years - until they told me I should only have been on it one or two (WTF??). I'm only 37, and i already have osteopenia. Early osteoporosis!
Take lots of calcium and do lots of exercise!
Other than that? I LOVED it! it was my "vaccine" - a shot in the butt every three months, and I was safe. And yes, it WAS still effective with antibiotics.