Everyone reacts to medications differently, but my experience with Zyprexa was not a good one. It made me gain about 60 pounds. The worst part was that it did not help my moods. I was even more depressed because I did not like the way I looked. My pdoc several years later told me that they found out that zyprexa turns off the part of your brain that tells you that you are full. So be very carefull.