I've been on Wellbutrin for a number of years. Mostly on 300mg. And only on XR.
I went to 450mg for a while, but I think it made me very angry and short-tempered.

My cognitive functioning is terrible, but I don't know what to blame as I am on a number of meds.
Funny that yesterday I started my period and I was a monster. I was working with horses and lost my cool. Ended up throwing things around (Not at horses nor people, but just out of pure frustration). I ended up being run over by a horse, kicked by another and fell off another (In all fairness, she was a horse that we had just backed, so she was nervous herself). I ended up taking an Ativan halfway through the afternoon.
I haven't seen myself in such a state in a long time. I don't know if it is Wellbutrin related as such. I am not usually so affected by PMS, so I also don't want to blame that alone.