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A long time ago, the first med I tried was an old tricyclic, Imipramine, & it was like a miracle. Brought me right up & out of a deep, dark place I’d never experienced before. But its side effect of constipation was crazy; once a week was bizarre. Having said that, it never bothered me or caused any kind of discomfort.
Nothing I've been on since that first time has ever had the same dramatic result.
For this last depressive episode, Prozac & Latuda were added to Effexor. I believe it has finally brought me up & out, & that I've stabilized.
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