I was on both Lamictal and Topamax. Here is what I experienced:

Lamictal: Very painful mouth sores (I'm prone to them though) and these stopped immediately after transitioning to Topamax. I was also angrier at night much like I experienced taking Wellbutrin.

Topamax: Best advice is to take this in the evening when you do not need to focus. I do have ADD and take Adderall and Prozac for depression already but this drug put me in a state of complete fog.

I couldn't put words together, I zoned out at work and in fact, I am way behind now because of that. This is mainly when I took it during the day (25mg 2x per day). Switching to nighttime helped a little but now that I have been off of this for a few weeks now, I feel much much better and can work, focus etc.

Also, I hesitate to post this because I don't know for sure if either of these drugs caused this but I developed purplish-dot like spots (some raised and most not raised) in the genital area.

I have vascular issues so my OB said it is probably related to that but honestly, this has NEVER EVER happened to me before taking either of these drugs.

I've seen my OB twice about this and she says they are nothing more than the raised blood clot like type bumps we get on our arms or legs and not an STD of any kind.

I'm waiting to see if these disaappear as they have not yet. Again, it may not be the medicine causing these but I didn't have them ever in my 37 years on this earth until I started on these two drugs.

Hope this helps