It took me 70 med combinations (dose changes not included) and well over 40 meds to find something that works. It's not perfect but it does work and my cycling is mild compared to before now. It took going to the "last resort" drug, clozaril, but clozaril helps me, especially combined with gabapentin (which I used to take without thinking it did much.Weird.). I have a mild depression going now and that's the only "big" (it's not very big) thing I've had since starting it in February.

I know how hard it is and how frustrating when meds don't work and then it compounds the frustration when that happen repeatedly but the right combination is out there, it just takes time to find it. And that is so hard but it's worth it.