I know this is an older thread, but I wanted to share my experience with Topamax which I use to control my Binge Eating.
It worked amazing for me at first, but my body eventually became used to it and I had to increase my dosage. I went so high 300mg that the side effects were too much to handle and I weaned myself off the drug. Then my appetite came back with a vengeance. I put on a fair amount of weight going off of Topamax. It wasn't until I went back on, the pounds came off. I still have cravings, I still go crazy at times, but it would be worse if I weren't on it. The sad part (for me anyway) I get so used to the medication that the effects wear off and the cycle repeats within about a year or so. I am very active, so I try to manage my weight also by working out.
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