It is very difficult when she is poisoning your mind about this guy and probably doesn't even realize it. I had this happen. My suggestion would be to tell you that it does make you not like him when she tells you these things. 22 is still very young. Hopefully things will get better as she matures.
I'd probably be most worried about a pregnancy at this point, but no doubt, you'll get blasted if you mention this subject.
Is there another trusted adult in her life that you can have help you?
I agree with Bill3's suggestions, they are right on. Good luck and big hug!