I was on a few meds both with and without mood stabilizers. They were pretty different in terms of ativation with the mood stabilizers; it wasn't a problem. I'm remembering Effexor specifically and it was much better with mood stabilizers with it. I had to go off it for some reason (I think I was having blood pressure issues???) but it did help and did not make me feel agitated all the time like it did when it was just Effexor.

Good luck!