Hi t11, I'm so sorry you're feeling along. Believe me, you're not alone.
I've been on Zoloft twice in my life. Neither time did I experience the negative side effects you've described. One exception to that: When I went from 150mg to 200mg I experienced anxiety, so I dropped the dose back down.
It seems to me that you should be feeling better by now, not worse. 3 weeks is a long time. Have you discussed the way you're feeling (from the Zoloft) with your doctor?
I'm thinking that starting out at 50mg was too much, too soon.
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