To begin with, I would like to say,
Our World needs more People like you! Your interest in Your Friends struggles shows great compassion.
From perspective of someone who suffers from Symptoms of (ASD), Not yet diagnosed!
I'm not the Expert!
I think you are on to something,
but your friend may or may not have a clue about the cause of these problems, or be afraid to confront them?
Your Friend needs people like you in Her life!
I might ask her what she knows about it, and see if She has an opinion about it!
Tell her you think one of your friends may have it, and you don't know how to Start the Conversation?
Ask her what She would Do?