I believe that is possible.
A few years ago I was diagnosed with Tachycardia. Did testing to figure out why my heart had suddenly started beating so quickly. It wasn't heart-disease related. We just couldn't figure out what was going on. Eventually, we tracked it down to my mental illness. It had started some time after my panic disorder decided to rear its ugly head back up. The constant anxiety, my mind and body were just pushing adrenaline and somehow it got switched to 'non-stop'.
Mental can cause physical. This has been well documented. Depression can wreck havoc on your body. Perhaps there is some way it switches on your immune system and the related hormones so that they are always on high alert, much like the prefrontal cortex in those with anxiety. From there, with the body being so interconnected, it's like a series of switches.