Well... the Skeezyks doesn't take any. I'm also on Psych-Central's sister website: NeuroTalk. And several members over there have recommended magnesium supplements to me. I don't know. I'm skeptical. For one thing... the supplements industry is pretty-much completely unregulated. And it seems like any time this stuff is tested, what's actually in the bottle seldom adheres to what it says on the label. Also, if you take more than your body needs, then the excess just ends up in the toilet, from what I understand. At one time, I used to take the multi-vitamin Centrum. But I never felt like it made any difference in the way I felt.