Thank you so much for your thoughtful reply! I am starting to wonder if the beta blocker can be causing the insomnia, although it didn't the last time I was on it. I actually am looking for another doctor sorta, lol! The beta blocker is prescribed for occasional heart palpitations, which happen with panic. I was on them originally for a month and a half, and then stopped and I was okay until this all started again. I agree that I'm in a cycle- low sleep = more anxiety = worse sleep because I obsess over it. When I get enough sleep (at least 5-6 hours, more is better of course) I am okay the following day and sorta think the Zoloft is working. Recently I had a bad night of no sleep (Thursday night, got like 2.5-3 hours) but the next day, I forced myself to function and I was as human as possible. And I wasn't as worried as I have been when this happens, which I attributed to the Zoloft. This is why I think jumping to 100mg is a bad idea. I am certain my doctor would not prescribe any z drugs like lunesta or ambien because of their addictive nature, he shamed me for taking lorazepam that I had from an ER doctor for a week when this all started and I couldn't sleep. It was the only thing that helped. He made me think I got dependent on it and I'm still worried that was part of the problem - that maybe I'm withdrawing from it. I took it 6 times across two weeks, and it's been almost three weeks, so who knows. Anyway moral of the story is, still trying to figure out!