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Old Sep 10, 2016, 11:44 PM
triplewater11 triplewater11 is offline
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Member Since: Aug 2016
Location: CA
Posts: 102
Quote:
Originally Posted by Skies View Post
I was really distrubed by your post, so I looked something up:

Drug Interaction Tool | University of Maryland Medical Center

I don't know what beta blocker you take, so I only checked 2, but they both had medium interactions with zoloft, but if you smoke, the interaction was severe and potentially dangerous.

Removing the smoking but adding Trazadone, the interaction is labeled as severe, and this only between Trazodone and Zoloft-it won't evaluate all 3 together.

Quote:
PROPRANOLOL - Propranolol (Injection)
TRAZODONE HYDROCHLORIDE - Trazodone (By mouth)
ZOLOFT - Sertraline (By mouth)

High Interaction Potential
Drug-to-Drug

TRAZODONE HYDROCHLORIDE (TRAZODONE HYDROCHLORIDE) and ZOLOFT (SERTRALINE HYDROCHLORIDE)
Taking sertraline together with trazodone may increase the risk of adverse effects, including problems with your blood pressure, body temperature, muscles, and thinking. Using sertraline together with trazodone is usually not recommended, but may be required in some cases. If you are using both medicines together, your doctor may change the dose or how often you use one or both of the medicines. It is important to tell your doctor and pharmacist about all other medicines that you are using. Call your doctor if you feel weak, have a rapid or fast heart beat, feel unusually restless, have a fever, or have trouble moving your arms and legs. Do not stop using your medicines without talking to your doctor first.

Those interaction tools are not necessarily followed to the T, but it's a good way to see if your doctor knows what he is doing and to keep yourself safe.

Beta blockers can also cause Hyponatremia and hyperkalaemia, some of which may mimic anxiety symptoms, and hyperkalaemia can wake you up at night with cardiac event and and metabolic acidosis causing heart palpitations.

Cardiovascular medications - beta-blockers | University of Maryland Medical Center

And here are nutrients depleted by beta blockers:


Cardiovascular medications - beta-blockers | University of Maryland Medical Center
Thank you for your thorough response! What disturbed you about my post? I hope it didn't upset or trigger you! I appreciate your research. I too was worried about doing Zoloft + trazodone because of the serotonin syndrome. I was reassured by my doctor and the pharmacist that I would be okay and lots of people do this. I typically take these meds many hours apart when I do use trazodone for sleep. I am not a fan of the beta blockers, either. I did not want to go on them to begin with in May. I was originally only on them for a month or two and went off, and after panic week 2016 I went back on. I am worried they maybe affecting my melatonin! It's hard to say since they didn't before and my sleep problems started before I went back on, but who knows. Maybe I need to try taking all my meds in the morning. Right now I space it out- beta blockers (metoprolol ER 25mg) at lunchtime, losartan 50mg (blood pressure med) at dinner, sertraline 50mg in evening. I changed sertraline from morning to evening to see if it would help with sleep. Thought a reboot might work. I really hate being on all these meds. Two years ago, I only took sertraline 50mg and I was doing super well. Last year my stress exploded, started with high blood pressure then random health issues which made health anxiety surge. I wish my doctor had tried to figure out why my blood pressure was high (maybe anxiety!) instead of starting this with the losartan script. My husband and I think the losartan affected me badly and triggered some off things, but we don't know for sure. Anyway, I am looking for a new doc! The other thing Is my husband and I have the same dr and my husband has to take blood thinners because he had a PE (pulmonary embolism) last year. No one ever figured out why this happened, but now he's on these blood thinners that make him bleed and other side effects and this is another thing that worries me. I think my doc is big on symptom management and not figuring out underlying causes. Maybe I sound obsessive but I wish doctors thought more about wellness and not "lack of symptoms." My therapist suggested my husband see a hematologist and I'm trying to get him to go. Anyway just another thing I am unhappy with about my dr! Sorry this was so long! you guys are really helpful though!