I generally go with generics, however, Wellbutrin I pay for the brand name. The generic Wellbutrin XL gave me insomnia, extreme anxiety, and heart problems. I ended up in the hospital with palpitations, tachycardia, hypertension, and a partial heart block. Not a good time. I've heard that the generic extended release doesn't release properly, or the same way as the brand name or something. Once I switched back to the brand name Wellbutrin, I was fine.

"They" say that generics are exactly the same, and as far as the actual active ingredient is concerned, that's true. But generics and brand names have different fillers, binders, and coatings, and those actually can affect people differently.