I have to agree with hopeless. If I miss one or two days of meds, I do put myself in danger of a hypo-manic episode. But I usually catch it well before that happens. Nowadays anyway. I think I used to want that up feeling, but now I'm happier being stable.

I'm sorry you're having such a hard time. It may or may not relate to missing one medication. As it is with so many med warnings, if you miss one med, take it the next time it is due, unless it is very close to when you missed it. Then take it right away

Like I said, I've never had such an extreme response, but everyone is different. I'm interested in what others have to contribute to the conversation. I suggest you talk it over with your doctor, nurse, or therapist. It also can depend on what kind of medication it is. Don't wait!!!