Seroquel works for me. I take 200 mg in the evening and it's also my prn at 25 mg. 1-3 times daily. It started out as my secondary medicine, then became my main one. I had food cravings and weight gain before taking it, but became motivated to lose weight and joined Weight Watchers 5 months ago. At first the drowsiness was something to contend with, but my body has adjusted, and my experience feels more like being settled down. It's interesting to hear about all the variety of experiences we have taking the same medicines.