My mother takes Zyprexa and Effexor. She's been on antidepressants so long that only the Zyprexa works. She initially put on 50 lbs within the first few months of taking them, and is up to a total of 80lbs.

She is concidered diabetic because her blood sugar is constantly above 120 (used to be concidered borderline but now either you are or you aren't apparently). She is on an oral diabeties med and has to watch diet and exercise.

The doctor has tried to take her off the Zyprexa several times, she does loose the weight blood sugar is good, but is suicidal. So she stays on the Zyprexa. She is on a fine line right now too because the doctor says anymore weight gain and he won't write the Rx for the Zyprexa anymore.