As you can see in my signature, I'm Bipolar 1 and take a small dose of Celexa as an AD. Others have made me manic, but I've done really well on this one. Of course, I'm on a mood stabilizer as well as two APs so that pretty much squashes any potential for mania. But I tried twice to get off the Celexa and was absolutely miserable, so my pdoc put me back on it for the duration. YMMV.