I recently started it myself. It is working great for me, my main problem with the Depakote besides the weight gain was the zombification/extreme grogginess what followed. Lamictal does none of that to me, feels like I can live a somewhat normal life now. As for titration I had to increase dosage quicker as Depakote was running out and Depakote withdrawal is no fun believe me. Took 25 first week, upped it to 50 second week, then after saw my doc and jumped to 100. No rash so I'm happy.