Cymbalta (& its generic equivalent) was the best antidepressant (for me) I ever took. (I started out on the name brand & then switched to the generic when it became available.) I was on the maximum recommended dosage & there were few side effects. One thing I did notice, after I had been on it for a while, was I seemed to develop some mild jerkiness in my hand & arm movements. However, I'm an older person & that may have had something to do with that.

I wouldn't say that the Cymbalta, or it's generic equivalent, kept me from being depressed entirely. But it "kept a floor under me", so to speak so that I never sank too low. I went off of it when I changed insurance plans & my out-of-pocket cost skyrocketed. When I went off of the generic equivalent I tapered off over the course of 2 weeks with very little trouble.