I have noticed that smoking lessens the side effects of my medications. I smoke about 60 cigs per day. I did actually did find a doctor that knew about the smoking/side effects thing and there are even a couple of studies floating around about it, but I don't remember where. You could try finding the studies using googlescholar.com you probably have to pay to read the study but you can read the abstract for free which is usually very helpful.

Anyway I guess my point is I really need to quit but don't know how I would do with increased side effects.