I take adderall, and I think it's similar to Vyvanse.
I have bipolar, and the low dose I am on does not interfere with mood swings.
I still go thru big ups and big downs not related to the stimulant.
But, my Dr said to cut back on it if I feel like it's causing me to become hypo or manic. (10mg 2x daily to 5mg 2x daily for example)